Ndibwino liti kuchokera pamankhwala ochepetsa thupi - Glucofage kapena Metformin?

Metmorphine ndi m'gulu la mankhwala amkamwa hypoglycemic. Awa ndi mankhwala a shuga a greatuanide grade. Imapezeka mwanjira yozungulira, mapiritsi a biconvex, enteric yokutidwa ndipo amachepetsa shuga. Chofunikira kwambiri ndi metmorphine hydrochloride ndi zotuluka - povidone K90, wowuma chimanga, crospovidone, magnesium steart, talc. Chipolopolocho chimakhala ndi methaconic acid ndi methylryacoplate copolymer (Eudragit L 100-55), macrogol 6000, titanium dioxide, talc.

Amalembera mtundu wachiwiri wa matenda a shuga 2 mellitus kawiri: pakusapezeka kwa ketocidosis komanso kuphatikiza ndi insulin chifukwa cha kunenepa kwambiri.

Kuchepetsa thupi msanga ndi metmorphine?

Vuto la kunenepa kwambiri komanso kunenepa kwambiri likukula kwambiri chaka chilichonse. Uwu ndi mliri wa zaka za zana la 21. Anthu mamiliyoni ambiri amalota zochepetsedwa komanso kuchepa thupi. Asayansi ambiri akuyesetsa kuthana ndi vutoli, koma njira yodziwikiratu sizipangidwa. Choyamba, ndikofunikira kumvetsetsa momwe amapangira mapangidwe owonjezera. Mutha kudziwa zomwe zikuchititsa. Zinthu zambiri zimathandizira owonjezera, ena omwe timatha kuwalamulira, pomwe ena samatengera ife:

1. Hypodynamia - kuoneka kwamafuta amthupi chifukwa chokhala phee.
   
2. Kuchuluka kwa maselo am'mafuta ndi malo omwe amasonkhanitsidwa zimadalira chibadwa chamtsogolo, amapanga zaka 18 ndipo amakhala osasinthika m'moyo wonse.
   
3. Zakudya zolimbitsa thupi. Kudya mopanda tanthauzo ndi chizolowezi chovuta kusiya.
   
4. Kunenepa kwambiri ndi mnzake wa matenda a endocrine. Monga kuchepa kwa ntchito ya endocrine ya chithokomiro, kusakwanira kwa mahomoni ogonana.
   
5. Anthu ambiri "amawugwiritsa ntchito" kuti apirire kupsinjika. Osalandira chakukhutira, amadya chakudya chochuluka kwambiri.
   6. Kusowa tulo kungathenso kukhathamiritsa thupi.
   

Zizolowezi zamadyedwe, moyo, kusewera masewera sizotsimikizira nthawi zonse kuti munthu amakhala wonenepa. Metabolism ndi dongosolo lovuta m'njira zambiri zomwe kapamba amalamulira. Kuwerengera kwa glucose ndi insulin m'magazi zimatengera chiwalo ichi. Pali mankhwala angapo omwe adapangidwa kuti azilamulira izi.

Kodi mankhwala a metmorphine amachepetsa bwanji ntchito?

Mwa chibadwa chake, mankhwalawa sakhala a lipolytics, amachepetsa kuchuluka kwa shuga m'magazi, ndipo chifukwa chake amachepetsa chilakolako ndi kulakalaka maswiti. Yogwira yogwira imalepheretsa mayamwidwe chakudya, chifukwa pali kuchepa kwa calorie tsiku lililonse, kuthamanga kwa oxidative njira lipid minofu, kuchotsedwa kwa mafuta m'thupi ndipo, chifukwa, kuwonda ndi subcutaneous mafuta. Thupi likalandira mankhwala ochepetsa thupi, metmorphine, minofu yake ya minofu imayamba kugwiranso ntchito mosungirako zomwe zilipo.

Momwe mungatenge metmorphine kuti muchepetse kunenepa?

Zomwe zimagwira zimalepheretsa gluconeogenesis m'chiwindi komanso zimachepetsa kuchuluka kwa glucose komwe kumachitika m'matumbo. M'mawu osavuta, chifukwa cha zochepa zomwe zimapezeka mu insulin ya mafuta, mafuta acids amachulukitsidwa mwachangu, kuchuluka kwa cholesterol ndi glucose m'magazi kumachepetsedwa, chakudya chamafuta chimakhudzidwa pang'onopang'ono, ndipo chilakolako chimachepetsa. Izi zimabweretsa ku normalization ndi kuchepetsa mafuta. Koma musaiwale kuti mankhwalawa ndi zingapo zotsutsana zomwe mungagwiritse ntchito:

• matenda owopsa
  
• matenda a impso
  
• mimba ndi mkaka wa m`mawere
  
• zaka zisanachitike 15 ndipo pambuyo 60 zaka
  
• uchidakwa wosatha
  
• lactic acidosis
  
• wodwala chiwindi
  
• kulephera kwa mtima
  
• matenda opatsirana
  
• kusowa kwamadzi
  
• malungo
  
• zigawenga.
  

Komabe, metmorphine imangothandiza pamodzi ndi zingapo zoyambitsa. Choyamba, musaiwale kuti mankhwalawa ndikugwiritsidwa ntchito mosavomerezeka kungayambitse zovuta. Kuti mupewe izi, muyenera kumvetsetsa kuti mulingo wa metmorphine wochepetsa thupi ndizovomerezeka.

Zakudya mukamamwa metmorphine chifukwa cha kunenepa

Zotsatira zake zitha kuwonekera pokhapokha malangizo ogwiritsa ntchito a metmorphine akaphatikizidwa ndi zochitika zolimbitsa thupi komanso zakudya. Ndikofunikira kwambiri, chifukwa ngati simutsatira chakudyacho, madyererowa samangothandiza, komanso amabweretsanso mavuto ambiri.

Choletsedwachi chimaphatikizapo zipatso zotsekemera, shuga ndi zonse zomwe zimaphatikizidwapo, confectionery ndi ophika buledi, nyama ndi mkaka ndi mkaka wowawasa, zipatso monga pompopompo, masamba otentha, mbatata, pasitala, mpunga woyera. Dulani mchere ndi zonunkhira.

Kodi siofor kapena metformin yabwino kwambiri yochepetsa thupi?

Metmorphine ndi cholowa m'malo mwa Siofor. Ndi mankhwala dzina lake padziko lonse lapansi matenda ashuga. Ndiwofanana m'njira zawo ndi kapangidwe kake.
Aliyense angathe kugula mapiritsi. Mtengo wa metmorphine wochepetsa thupi ndiwovomerezeka ndipo zimatengera ma CD, komwe mugule ndi dera liti. Mu pharmacy wokhazikika, mtengo umakhala wokwera kuposa pa intaneti.
Mtengo wa 500 mg umakhala ma ruble 150 pa paketi 30 yama PC.
Mutha kugula 1000 mg (60 ma PC.) Kwa ma ruble 350.
Mtengo umatanthauzanso ma phukusi: 50 ma PC. pafupifupi mtengo kuchokera ku ma ruble 250. Iyenera kukumbukiridwa mukamagula mankhwala omwe amagulitsidwa ndi mankhwala.

Zotsatira zoyipa za metmorphine kuwonda

Kuphwanya malangizo azakudya kungakulitse chiwonetsero cha zovuta. Choopsa kwambiri mwa iwo ndi lactacitosis (kuchuluka kwa lactic acid mthupi). Mutha kukumvanso nseru ndi kusanza, kusasangalala pamimba, hypovitaminosis (malabsorption), kutopa msanga, kupuma kwambiri komanso kupweteka, kutulutsa m'mimba, mpweya m'mimba, kutsekemera kwazitsulo mkamwa komanso ngakhale kusazindikira. Nthawi zina, vuto lotchedwa megaloblastic anemia (kuchuluka kwa maselo amodzi m'magazi), hypoglycemia (kuchepa kwambiri kwa shuga m'magazi), zotupa pakhungu.

Munthu ayenera kusankha pa kugwiritsidwa ntchito kwa metmorphine pakuchepetsa thupi, koma munthu asayiwale kuti chida ichi ndi choyenera kwa iwo omwe alibe matenda omwe atchulidwa mndandanda wa contraindication. Mankhwalawo pawokha samuphwanya chilichonse, koma angathandize kuwonjezera chakudya.

Zotsatira zoyipa sizitha kupewedwa: kutulutsa magazi ndi kutsekula m'mimba. Kuchepetsa kudya za kabohaidreti komanso kuchepetsa kugwirira kwa phala tsiku ndi tsiku kumachepetsa mavuto, koma kudya pang'ono kwa carb kumapangitsa kudzimbidwa. Muyenera kuganizira zamomwe mungathane ndi mavuto am'matumbo, osati zokhudzana ndi zakudya komanso masewera olimbitsa thupi.

Akatswiri sanapeze mgwirizano pazoyenera kugwiritsa ntchito metmorphine kuti achepetse thupi. Ena amanenanso kuti limachita bwino ndipo amati ndi anthu onenepa kwambiri. Ena akutsimikiza kuti kulandiraku ndi kowopsa. Kafukufuku sanamalizebe mpaka pano, koma titha kunena motsimikiza kuti zomwe zikuwonetsa kugwiritsa ntchito metformin pakuchepetsa thupi ziyenera kuganiziridwa payekhapayekha.

Ma netiwewa ali ndi mawunikidwe okwanira omwe anganene kuti mutha kuchepa thupi nayo. Amakuuzani zomwe mukufuna musanakumane ndi akatswiri ndikutsatira malangizo onse. Olembawo amafotokozanso chifukwa chomwe adasankhira ndi momwe njirayo idayendera. Nthawi zambiri, kusankha kumagwera mapiritsi a kudya a metmorphine chifukwa cha matenda ashuga, matenda a endocrine system, kusokonekera kwa mahomoni, komanso ukalamba. Pafupifupi, 1 mpaka 5 makilogalamu amatenga mwezi umodzi ngati atsatira malamulowo, makamaka omwe akukhudzana ndi zakudya. Ambiri mwa ndemanga akuti mankhwalawo sanathandize ndipo ndi osathandiza pakugwiritsa ntchito. Anawathamangitsa ndi ziwengo ndi mavuto.

Zambiri zamankhwala oyamba

Hypoglycemic wothandizila kukonzekera pakamwa monga mapiritsi. Glucophage imakhala ndi metformin hydrochloride monga gawo lake lalikulu. Kuphatikizika kwake kumadalira mlingo womwe umasankhidwa ndipo ukhoza kuchokera ku 0,5 g mpaka 1 g pa unit. Kuphatikiza apo, Glucophage imapatsidwa zina zowonjezera:

• Opadra KLIA kuti apange chipolopolo (filimu),
• Mmagnia wakuba,
• Povidone K 30.

Kuphatikizika kwa zosakaniza za mankhwala sikuyambitsa kupangidwira kwa insulin. Zodabwitsazi sizikhudza momwe munthu aliri mu mawonekedwe a hypoglycemic. Mankhwalawa amachepetsa kuchuluka kwa glucose mosasamala nthawi yakudya komanso chakudya. Zotsatira zamankhwala, kuyendetsa ma membrane oyendetsa glucose kumayenda bwino; sikuti amatengeka kwambiri m'matumbo. Wodwala amapezeka ndi kusintha kwamphamvu kwa insulin minyewa, ndipo glucose amapangidwa m'chiwindi pang'onopang'ono.

Njira zonsezi zimakhudza osati thanzi la wodwalayo, komanso kulemera kwake. Madokotala pakapita maphunziro ambiri apeza kuti mapaundi owonjezera amachoka pang'ono kapena amakhala osasinthika pamlingo womwewo, zomwe zilinso zabwino kwa wodwalayo.

Kukhazikitsa kwa mankhwalawa Glucofage kumawonetsa kuti mankhwala amalembedwa kwa anthu odwala matenda ashuga a 2, ngati tebulo lamankhwala lingagwiritsidwe ntchito silikupatsani zotsatira zomwe mukufuna ndi masewera. Gwiritsani ntchito odwala omwe ali ndi kunenepa kwambiri. Kulandila kutha kuchitika mwa njira yayikulu komanso yokhayo ya mankhwala kapena kuphatikiza ndi insulin ya ana kuyambira zaka 10 komanso limodzi ndi mankhwala a insulin ndi hypoglycemic zochizira odwala akulu.

Zambiri pazomwe zikuchitidwa ndi Metformin

Mankhwala othandizira odwala matenda a shuga ndi mankhwala a pakamwa a hypoglycemic. Chopanga chachikulu ndi metformin hydrochloride womwewo mu mtundu womwewo wa mtundu wakale. Mndandanda wazopeza zimasiyana pamakonzedwe awa. Chifukwa chake, mu mapiritsi awa muli zinthu monga:

• Propylene glycol,
• Povidone
• Talc,
• Wowuma chimanga
• Titanium dioxide ndi ena

Polyethylene glycol 400 ndi 6000, komanso hypromellose, amagwiritsidwa ntchito kupanga chovala cha filimuyo. Mankhwala amathandizidwanso kwa odwala omwe ali ndi mtundu wofanana ndi matenda a shuga 2, koma amtundu wa insulin wokha, ngati palibe chifukwa chochita zolimbitsa thupi. Amagwiritsidwa ntchito ngati othandizira othandizira pochizira komanso mapiritsi ena a hypoglycemic.

Kuyerekezera Mankhwala

Ngati mukuganiza zomwe zingakuthandizeni kuchepetsa kunenepa: Metformin kapena Glucofage, muyenera kuganizira kuwonongeka kwachiwiri. Mankhwala amatha kuzolowera zochitika zina. Ndiye kuti, Glucophage imapanga chiwonetsero cha mphamvu yake ya hypoglycemic pokhapokha kuchuluka kwa glucose m'magazi a anthu kukwera. Ngati chizindikirochi ndichabwinobwino, palibe chifukwa chotsikirira, ndiye kuti thupi silimachitanso chimodzimodzi.

Kusiyana pakati pa mankhwalawo kuli mkati mwake momwe kukulira kwamphamvu kwa minofu yaumunthu kum insulin. Chifukwa chodziwikiratu kwa zinthu zomwe zimagwira, kuyamwa kwa glucose ndi thirakiti lam'mimba ndikutsekedwa, zomwe zimapangitsa kuchepa kwa magazi. Madokotala amati mankhwalawa Glucofage amagwira ntchito mwachangu, zomwe zimapangitsa kuti minye ya wodwalayo isakanikirane ndi zigawo zina za mankhwala.

Metformin, nayenso, siyitsogolera pakupanga insulini, motero glucose satsika kwambiri. Njira yodziwikitsira ndizosiyana ndi zomwe zimagwiritsidwa ntchito ndi mankhwala akale. Zotsatira zake, metformin hydrochloride imakhala munjira yopanga shuga, kuletsa njirayi, yomwe imapangitsa kutsika kwa kuchuluka kwa zinthu. Nthawi yomweyo, kuchuluka kwa glucose amene amakhala m'magazi a wodwala akamadya kumachepa. Zonsezi zimakhala cholepheretsa mapangidwe a matenda a shuga, kupatula kukula kwa chikomokere mwa iye.

Chifukwa chake, poganizira zamomwe zimapangidwira mankhwala a Glucofage ndi Metformin, zitha kukhazikitsidwa kuti kusiyana kwake ndi kachitidwe ka zochita pa thupi la munthu. Koma izi ndizotalikira kusiyanasiyana konse. Madokotala nthawi zambiri amapereka metformin kuti alembe 1 ndikulemba matenda ashuga a 2, anthu omwe ali ndi kunenepa kwambiri. Mu mankhwala, kuphatikiza kwa mankhwalawa ndi insulin kumapezeka.

Mukamasankha njira yamankhwala, katswiri adzaonetsa mawonekedwe a Metformin - kupewa mavuto komanso kukulitsa kwa matenda a mtima.

Ndipo tsopano mwatsatanetsatane ku funso loti Glucophage amasiyana bwanji ndi Metformin. Zikuwoneka kuti ndizofanana zomwe zikuwonetsa: kusowa kwa zotsatira za chithandizo cha matenda ashuga komanso kugwiritsa ntchito zakudya, zolimbitsa thupi, koma matenda a mtundu 2 wokha. Kuphatikiza apo, Glucophage Long imakhala ndi mphamvu yayitali, yomwe imawonetsa pang'onopang'ono zomwe zimagwira ndipo zimakhudzanso thupi la munthu. Opanga samalepheretsa kugwira ntchito kwa mankhwalawa chifukwa chosiyana ndi mankhwala a Metformin omwe amagwira ntchito mwachangu.

Mankhwala Glucophage Long amawoneka muubwino wambiri:

• Kumanga michere ya protein,
• Matendawa mabiliyoni ambiri,
• Mothandizidwa amachepetsa kuchuluka kwa shuga m'magazi,
• Amachotsa mavuto ndi zovuta zama metabolic.

Koma ngakhale mndandanda wosangalatsa woterewu samapangitsa mankhwalawo kukhala osiyana ndi ena. Satha kusintha chakudya chokwanira kwa wodwala matenda ashuga.

Mtengo wa mankhwalawa umavutitsanso odwala, chifukwa Metformin ndi yotsika mtengo. Koma okwera mtengo kwambiri ndi Glucophage Long. Ndi dokotala wokhayo amene angadziwe zobisika za kusiyana pakati pa mayina ogulitsawa pafupifupi chithandizo chofanana. Kusiyanitsa pakati pawo ndikochepa, koma cholinga chake chimatengera magawo angapo a anthu:

• Mtundu wa matenda ashuga
• Gawo la kunenepa kwambiri,
• M'badwo wodwala
• Kuphatikizika kwa mankhwala omwe amayenera kumwa panthawi ya mankhwala,
• Mayendedwe ophatikizidwa
• Hypersensitivity kwa wotchuka wina, etc.

Kuletsedwa kotheratu

Mankhwala onse omwe amapangidwa pamaziko a metformin hydrochloride ali ndi zotsutsana zingapo komanso zoyipa, ndipo kugwiritsa ntchito molakwika kumatha kuyambitsa mavuto ena. Iyenera kuthandizidwa makamaka ngati mayi angagwiritse ntchito mapiritsi a zakudya izi.

Ngakhale pali kusiyana pang'ono pakati pa mankhwala Glucofage ndi Metformin, onse awiriwa amatha kuyambitsa mavuto:

• Kuthekera kwa matenda a anorexia kukuchulukirachulukira,
• Zimabweretsa kuchepa kwakukulu kwa vitamini B, ndipo izi zimakakamiza wodwala kuti atenge mankhwala ena owonjezera,
• Zizindikiro zoyipa (kutsegula m'mimba, kusanza, kupweteka m'mimba),
• Chiwopsezo chotenga ma pathologies am'mimba,
• Matenda a pakhungu (zotupa, mafupa),
• Anemia
• Kusintha kwa kukoma (mwachitsanzo, kukoma kwachitsulo).

Kukhazikika kwa mankhwalawa kumapangitsa kuti thupi lizikundana, ndipo izi zimapanga lactic acidosis. Mkhalidwe wa matenda a impso ukuwonjezereka. Simungathe kupereka mankhwalawa kwa amayi apakati ndi amayi omwe akuyamwitsa. Ndi kusalolera chimodzi mwazigawo, mankhwalawa samamwa. Mankhwalawa amadziwikiratu chifukwa cha kulephera kwa mtima, ndimomwe amalembera m'mbuyomu.

Khalidwe la Metformin

Metformin ndi mankhwala othandizira odwala matenda ashuga malinga ndi zomwe zimagwira. Mapiritsi amapezeka mu mlingo wa 500/8/10000 mg.

Zosakaniza zina ndi magnesium stearate, talc ndi wowuma. Makampani angapo amatulutsa mankhwalawo. Mwachitsanzo, Teva (Poland) ndi Sandoz (Germany).

Kuyerekezera Mankhwala

Kuyerekeza Glucofage ndi Metformin kuyenera kuyamba ndikuti zochita zawo zimatengera chinthu chimodzi chomwe chikugwira.Ubwino ndi zovuta zonse zimachitika chifukwa cha metformin.

Mankhwala onse awiriwa amaphatikizanso zomwezi. Metformin imathandizira chidwi cha zotumphukira zolandilira ku insulin, zimapangitsa kuti glucose apezeke ndi maselo amisempha. Komabe, sizimakhudzanso zizindikiro zina za matenda ashuga, monga polyuria (kuchuluka kwa mapangidwe a mkodzo), komanso pakamwa pouma.

Metformin imakhala ndi phindu pa metabolidi ya lipid, kuwonda. Mankhwalawa amachepetsa kuchuluka kwa cholesterol m'magazi ndi LDL, omwe ndi mitundu yoopsa kwambiri. Zotsatira zoyesa magazi a glycated hemoglobin zimayenda bwino (chizindikiro ichi chiyenera kuyang'aniridwa).

Mukamagwiritsa ntchito mankhwala osokoneza bongo, chiopsezo chokhala ndi mikhalidwe ya hypoglycemic ndi yotsika kuposa momwe angatengere mapangidwe awo.

Njira zimasonyezanso chimodzimodzi. Mwachitsanzo, lembani matenda ashuga 2. Pankhaniyi, onse mankhwalawa amalimbikitsidwa kuti amwe pokhapokha ngati kunenepa kwambiri komanso kuchuluka koyenera kwa glucose m'magazi sikungatheke pokhapokha ngati mukudya zakudya zolimbitsa thupi komanso kuchita masewera olimbitsa thupi mokwanira. Mapiritsi amaloledwa kwa ana azaka zapakati pa 10, mlingo wokhawo womwe umaperekedwa kwa iwo.

Mankhwala onse awiriwa amatha kugwiritsidwa ntchito ngati prophylaxis ngati odwala ali ndi prediabetes, ngati kusintha kwa moyo sikumapangitsa kuti zinthu zikhale bwino.

Contraindication idzakhalanso yofanana. Mphamvu ya mankhwalawa imakhudza kusinthasintha pamlingo wa lactic acid, chifukwa chake sagwiritsidwa ntchito ngati matenda a lactic acidosis.

Contraindication ndi:

• Hypersensitivity pamndandanda wa mankhwalawo,
• kuchitapo kanthu komwe ma insulin amalembera,
• chiwindi ntchito, kuphatikizapo chiwindi,
• matenda osiyanasiyana a impso ndi ma pathologies omwe amakhudza kugwira ntchito kwa chiwalo ichi, mwachitsanzo, matenda, matenda a hypoxia, kuphatikizapo omwe amapezeka ndi matenda a bronchopulmonary,
• uchidakwa wambiri ndi chiphe chakumwa chaukali.

Metformin ndi Glucofage satengedwa panthawi yoyembekezera komanso mkaka wa m'mawere. Kuti muchepetse zovuta, mankhwalawa sakhazikitsidwa masiku angapo maphunziro asanachitike pogwiritsa ntchito njira za wailesi.

Metformin ndi Glucofage satengedwa panthawi yoyembekezera komanso mkaka wa m'mawere.

Kuphatikiza apo, ngakhale kuti mankhwalawa onse amavomerezedwa bwino ndi anthu okalamba, kwa odwala azaka zopitilira 60 omwe akuchita ntchito yayikulu, metformin imatsutsana, chifukwa chochita chake chimayambitsa kukulira kwa lactic acidosis.

Zotsatira zoyipa za mankhwalawa zimakhalanso chimodzimodzi. Izi zikuphatikiza:

1. Mawonekedwe a Dyspeptic, kuphatikiza mseru, kusanza, kutsegula m'mimba, kubala komanso kupweteka kwam'mimba. Mukumwa mankhwala, kulakalaka kumachepa. Koma zinthu zonsezi zimadzichitira zokha popanda kudzipatula.
2. Lactic acidosis (mkhalidwewu umafuna kusiya mankhwala mwachangu).

Pogwiritsa ntchito nthawi yayitali, hypovitaminosis imatha kuphatikizidwa ndi malabsorption a mavitamini B.

Zotsatira zoyipa, kuphatikizapo zotupa pakhungu, ndizotheka. Ma antispasmodics ndi maantacid athandizira kuchepetsa mawonekedwe osafunikira ochokera kumimba. Nthawi zambiri, pazifukwa izi, madokotala amapereka mankhwala a Metformin ndi Glucofage kumapeto kwa chakudya, mosaganizira kuchuluka kwa mankhwalawa. Izi zimathandiza kupewa zizindikiro za dyspeptic.

Kodi pali kusiyana kotani?

Metformin imagwiritsidwanso ntchito ngati mtundu 1 wa shuga. Koma ngati ndi matenda a shuga a mtundu wachiwiri amatha kukhala ngati monotherapy, ndiye kuti pamenepa amagwiritsidwa ntchito limodzi ndi insulin.

Metformin imagwiritsidwanso ntchito ngati mtundu 1 wa shuga. Koma ngati ndi matenda a shuga a mtundu wachiwiri amatha kukhala ngati monotherapy, ndiye kuti pamenepa amagwiritsidwa ntchito limodzi ndi insulin.

Komabe, kusiyana kwakukulu kulipo pakati pa Metformin ndi mtundu wa mankhwalawo, monga Glucofage Long. Chowonadi ndi chakuti kwa omaliza mawonekedwe atsopano a metformin XR apangidwa. Cholinga cha akatswiri opanga zamankhwala chinali kuchotsa mavuto ofunika kwambiri omwe amatengera kutenga metformin wokhazikika, kutanthauza kusalolerana m'mimba. Kupatula apo, kugwiritsa ntchito mankhwalawa mobwerezabwereza, mavuto amangokulira.

Chizindikiro chachikulu cha mankhwala Glucofage Long ndikutulutsa pang'onopang'ono, komwe kumawonjezera nthawi yofunikira kuti pakhale magazi ambiri mpaka maola 7. Nthawi yomweyo, phindu la chizindikiro ichi palokha likuchepa.

Ponena za bioavailability, ndizokwera pang'ono kwa Glucofage Kutalika kuposa kutulutsidwa kwa Metformin mwachangu.

Ndi matenda ashuga

Zochizira matenda ashuga, mfundo yofunika ndiyakuti kangati patsiku muyenera kugwiritsa ntchito mankhwalawa. Chowonadi ndi chakuti nthawi zina odwala amatenga mankhwala angapo nthawi imodzi, ndipo ngati imodzi ya iwo ikuyenera kuledzera kawiri pa tsiku, ndizotheka kuti munthu awakane, kutsatira kwa wodwalayo kumakulirakulira. Metformin ndi Glucophage mu mawonekedwe awo apamwamba amaganiza chimodzimodzi.

Popeza Metformin ndi Glucophage ndi ofanana mu mawonekedwe omwewo, ndizovuta kudziwa kuti ndi mankhwala ati omwe angasankhidwa.

Komabe, Glucofage Long imatha kutengedwa nthawi imodzi yokha patsiku. Izi zimawongolera kutsatira kwa wodwala. Kuphatikiza apo, amaloledwa bwino ndi thupi. Kafukufuku akuwonetsa kuti kwa mankhwala monga Glucofage Long, pali chiopsezo chochepera 50% cha zotsatira zoyipa kuchokera m'mimba.

Chifukwa chamasulidwa pang'onopang'ono pazomwe zimagwira, mankhwalawa ndi othandiza kwambiri kuposa mitundu "yofulumira" ya Metformin. Zimakupatsirani mwayi wolamulira kuchuluka kwa shuga m'magazi komanso kumachepetsa mwayi wokhala ndi vuto la shuga.