Mapiritsi a shuga a m'badwo wotsatira ndi mankhwala osokoneza bongo a matenda a shuga a 2

Kuchulukitsa kwa shuga kwa mankhwalawa ndikulimbikitsa maselo a pancreatic kuti apange insulini, kusintha kuyamwa kwa glucose ndi minofu, potero kuchepetsa magazi ake. Amalepheretsa kupanga shuga m'magazi.

Mankhwalawa amachepetsa kagayidwe ka lipid, amachepetsa kuchuluka kwa mafuta m'magazi, amachepetsa magazi, amalepheretsa zovuta za matenda ashuga (retinopathy, mtima matenda).

Chifukwa cha kapangidwe kake kakang'ono kwambiri, mankhwalawa amatha msanga ndipo amadzaza pamaso pake m'mimba, ali ndi bioavailability kwathunthu.

Zizindikiro ndi mlingo

Type 2 shuga mellitus ndi kulephera kwa mankhwala antidiabetesic ndi kunenepa kwambiri.

Mankhwalawa amalembedwa ndi dokotala. Mlingo umakhazikitsidwa payekhapayekha, poganizira kuchuluka kwa shuga pamimba yopanda kanthu komanso maola awiri mutatha kudya.

Mlingo woyamba wa tsiku lililonse wa 1.75 mg wa mannyl ndi piritsi 0.5-1. Pang'onopang'ono onjezani mlingo kuti musinthe shuga. Mulingo waukulu ndi mapiritsi atatu patsiku.

Kuti muwonjezere mlingo, amasinthira ku mannil a 3.5 mg kuyambira pa mapiritsi a 0,5-1 patsiku.

Maninil 5 mg amayamba ndi mapiritsi 0,5 patsiku. Mukawonetsedwa, tsiku ndi tsiku mlingo umakulitsidwa pang'onopang'ono mpaka 15 mg. Mlingo wapamwamba sukulitsa kuchepa kwa shuga kwa mannyl.

Maninil amatengedwa theka la ola musanadye. Piritsi imatsukidwa ndi madzi osafuna kutafuna. Mlingo wa tsiku lililonse wa mapiritsi oposa 2 amagawidwa m'mawa ndi madzulo. Wonjezerani mlingo woyang'aniridwa ndi dokotala.

Ngati mulingo woyenera wa mankhwalawo sungagwire ntchito, funso lothandizira insulin ndi maninil likutha.

Zoyipa:

• mtundu 1 shuga
• achina,
• matenda ashuga, ketoacidosis,
• mawonekedwe a impso ndi chiwindi.
• mimba, yoyamwitsa,
• tsankho kuti sulfanilurea kukonzekera.
• Zotheka kuchitidwa:
• achina,
• Zizindikiro zam'maso
• thupi lawo siligwirizana

Maninil ayenera kuikidwa mosamala kwa odwala atatha zaka 60 (ngozi ya hypoglycemia), komanso kwa anthu omwe ntchito yawo imafunika kuti ichitidwe.

Momwe mungamvetsetse mayina a mankhwala omwe amachepetsa shuga ya magazi

Ndikukumbuseni, abwenzi, kuti mankhwala aliwonse ali ndi dzina lake lakunja lopanda mgwirizano, amatchedwa INN. Dzinali limanenedwa m'mawu osankhidwa ngati atatsitsidwa ku chipatala. Ndipo mayina omwe mumawawona mumasitolo akupanga ndiwo mayina ogulitsa amakampani azamankhwala. INN pa phukusi nthawi zambiri limalembedwa mzosindikiza yaying'ono pansi pa dzina la malonda. Nthawi zina mayinawa amanjana.

Chifukwa chake, sindinganene za wothandizila kutsitsa shuga wina, mwachitsanzo, maninil, koma za gulu la mankhwala motengera glibenclamide. Ndiponso, ndikupereka zitsanzo ndi fanizo la mayina amalonda ndi dziko la wopanga mankhwala ochepetsa shuga.

Ndikufuna ndiyankhule za gulu lirilonse la mankhwala ochepetsa shuga, koma ndisanatero ndidaganiza "kulengeza mndandanda wonse", ndikufotokozera gulu lililonse mwachidule.

Maninil - mawonekedwe omasulidwa

Manilin, chithunzi chake chomwe chikuwonetsedwa mu gawo ili, chili ndi zinthu zoyambira glibenclamide ndi mafilimu:

• Methyl hydroxyethyl cellulose,
• Lactose Monohydrate,
• Wowuma wa mbatata
• Magnesium wakuba,
• Silicon dioxide
• Dye Ponceau 4R.

Ndikosavuta kuzindikira zomwe kampani yaku Germany yopanga mankhwala Berlin-Chemie (Menarini Gulu): mapiritsi okhala ndi pinki tint ali ndi chamfer komanso mzere wogawa mbali imodzi. Kutengera mlingo, piritsi limodzi limatha kukhala ndi 3.5-5 mg wa mankhwala othandizira.

Patsamba lamankhwala, mankhwala atha kugulidwa ndi mankhwala. Ku Maninil, mtengo wake ndi ndalama zambiri - kuchokera ku 140 mpaka 185 ma ruble. Mankhwala safuna mikhalidwe yapadera kuti asungidwe, koma kufikira kwa ana ndi kuwongolera dzuwa kuyenera kukhala kochepa. Moyo wa alumali wam'mapiritsi ndi zaka 3, mankhwala omwe adatha amatha.

Kuthekera kwama pharmacological

Ntchito yayikulu ya glibenclamide ndikulimbikitsa β-maselo a islets a Langerhans, omwe ali ndi udindo wopanga insulin yawoyawo. Zochita za Β-cell ndizofanana mwachindunji pamlingo wa glycemia komanso malo ake. Mukatha kugwiritsa ntchito, mapiritsiwo amatengedwa mwachangu ndi makhoma a matumbo. Kuchuluka kwa kuchuluka kwa zomwe zili m'mimba ndi nthawi yomwe zimadzazidwa ndi chakudya sizikhudzidwa. Ndi mapuloteni a plasma, mankhwalawa amabwera ndi 98%. Kuchuluka kwa mulingo wake mu seramu yamagazi kumawonedwa pambuyo pa maola 2 ndi theka ndikufika pazomwe 100 ng / ml. Hafu ya moyo imakhala pafupifupi maola awiri, mutatengedwa pa os - 7 maola. Kutengera ndi chithunzi cha matenda, odwala matenda ashuga nthawi imeneyi amatha maola 8 kapena 10.

Mankhwalawa amaphatikizidwa makamaka m'chiwindi, akusintha mothandizidwa ndiopanda ma cell mu mitundu iwiri ya metabolites: 3-cis-hydroxy-glibenclamide ndi 4-trans-hydroxy-glibenclamide.

Zakhala zikutsimikiziridwa kuti ma metabolites samayambitsa matenda a hypoglycemic, atachotsa impso ndi ma ducts a bile kwathunthu mthupi masiku atatu.

Ngati chiwindi chikulephera, mankhwalawo amasungidwa m'magazi kwa nthawi yayitali. Ndi pathologies a impso ndi mkodzo, amachotsedwa pang'onopang'ono, nthawi yomwe zimatengera kuuma kwa magwiridwe antchito a thupi.

Makamaka, ndiofatsa modekha mawonekedwe aimpso kukanika, kukonzekera sikumakhazikika. Ndi creatinine chilolezo ≤30 ml / min, kuchuluka kwa kuthetsedwa kwa metabolites kumachepa, motero kuwonjezeka kwa msana wa mankhwala m'magazi. Mikhalidwe yofananira ndi Maninil imafuna kuti mankhwalawa atenge gawo kapena kutulutsa (nthawi zambiri, milandu ya basal insulin).

Maninil ndi ndani?

Mankhwalawa adapangira kuti azilamulira matenda a shuga a 2 (mawonekedwe osagwirizana ndi insulin). Mapiritsi amalembedwa kwa anthu odwala matenda ashuga kuwonjezera pakalibe kukonza zomwe zakonzedwa pambuyo poti asinthe (chakudya chochepa kwambiri cha carb, zolimbitsa thupi zokwanira, kukonza kulemera kambiri, kuwongolera zakukhosi, kutsatira kugona ndi kupuma).

Endocrinologist amalembera mankhwala, kuwerengera njira zochizira poganizira kadyedwe, zaka za odwala, gawo la matendawa, matenda amtunduwu, thanzi komanso mayankho a thupi pakumwa mankhwalawo. Mlingo umakhazikitsidwa potengera mbiri ya wodwala.

Mlingo woyambira nthawi zambiri umaperekedwa ngati osachepera - theka la piritsi lolemera 5 mg kapena 3.5 mg patsiku. Chidwi chachikulu pa kusintha kwa mlingo kumaperekedwa kwa odwala asthenic omwe ali ndi hypocaloric zakudya, m'mbiri yomwe imakhala ndi vuto la hypoglycemic, komanso anthu omwe akuchita ntchito yayikulu. Sabata yoyamba yolamulira ya glycemic tsiku lililonse imafunikira. Dosing titration imachitika malinga ndi umboni wa mita komanso mwakufuna kwa dokotala.

Mankhwala achire a Maninil pafupifupi 15 mg / tsiku, mapiritsi atatu a 5 mg kapena mapiritsi 5 a 3.5 mg.

Maninil atalowa m'malo mwa mankhwala ena a hypoglycemic, amawongoleredwa ndi kumwa poyambira. Pambuyo pakutha kwa mankhwala am'mbuyomu, mawonekedwe a glucometer ndi zotsatira za kusanthula kwamkodzo pazinthu zachilengedwe, popanda mawonekedwe a mankhwala, zimafotokozedwa. Zomwe thupi limayang'anitsitsa ndi osachepera mlingo - 0,5 mapiritsi a 3.5 kapena 5 mg. Kutsatira zakudya ndi zina zokhala ndi moyo wathanzi ndizovomerezeka. Pofuna kupewa zovuta, mlingo wa mankhwala watsopano umakulitsidwa pang'onopang'ono. Wodwala matenda ashuga ayenera kumuuza adotolo zonse zakusintha kwaumoyo.

Malangizo ogwiritsira ntchito

Maninil amalimbikitsa kuti mugwiritse ntchito m'mawa, musanadye chakudya cham'mawa, muzitsuka mapiritsi anu ndi kapu yamadzi. Nthawi zonse zikaposa 2 ma PC / tsiku, zimagawika pawiri Mlingo 2: 1. Kuti mupeze chithandizo chokwanira kwambiri, ndikofunika kumwa mankhwalawa nthawi yomweyo.

Zotsatira zoyipa

Malinga ndi malingaliro a WHO, pafupipafupi pazovuta zomwe zimachitika chifukwa cha mankhwala zimawunikidwa pamlingo wapadera:

• Nthawi zambiri - kuchokera 10%,
• Nthawi zambiri - kuchokera pa 1 mpaka 10%,
• Nthawi zina - kuchokera ku 0,1 mpaka 1%,
• Si kawirikawiri - kuchokera pa 0,01% mpaka 0.1%,
• Osowa kwambiri - mpaka 0,01% kapena milandu sanalembedwe konse.

Chiwerengero cha zochitika zoyipa kuchokera ku Maninil chimawerengeredwa mosavuta pagome.

Zosokoneza zowonekera nthawi zambiri zimawonedwa munthawi ya kusinthana ndi mankhwalawa ndikudziyendera nokha, popanda chithandizo chamankhwala. Matenda a dyspeptic mu mawonekedwe a vuto la mseru, kusanza, kutsekula m'mimba sikufuna kusintha kwa mankhwalawo komanso kumazimiririka pakapita nthawi.

Ngati pali mtundu wa ziwopsezo za ziwopsezo ku glibenclamide, pamakhala chiwopsezo cha intracranial cholestasis ndi zovuta mu mawonekedwe a kusweka bwino kwa chiwindi.

Matenda a pakhungu nthawi zambiri amasinthika, koma nthawi zina amatha kubweretsa chidwi chomwe chikuwopseza moyo wa odwala matenda ashuga.

Kuchokera ku Maninil, chifuwa ndi mavuto ena amatha kuwonetsedwa ndi kuzizira, kutentha thupi, zizindikiro za jaundice, kupezeka kwa mapuloteni poyesa mkodzo. Muzochitika zonse, kufunsa dokotala wofunikira ndikofunikira.

Nthawi zina, kuchepetsedwa kwa zosakaniza zonse zamagazi amalembedwa nthawi yomweyo. Mankhwala atathetsedwa, sizimangopita zokha. Kupha ziwopsezo ndizotheka ndi mankhwala ena omwe amachititsa kuti wodwala azikhala wodwala. Makamaka, utoto wa E124, womwe umagwiritsidwa ntchito popanga mankhwala, ndi wamphamvu kwambiri.

Maninil - zotsutsana

Mankhwalawa sanatchulidwe hypersensitivity ku zosakaniza za formula. Komanso sizikuwonetsedwa:

• Kwa ziwengo ku okodzetsa ndi mankhwala ena aliwonse a sulfonylurea, kukonzekera kwa sulfonylamide, phenenecid,
• Anthu odwala matenda ashuga a mtundu woyamba 1, omwe ali ndi vuto la β-cell,
• Ngati wovutikayo ali ndi metabolic acidosis, chikomokere,
• Amayi oyembekezera komanso oyembekezera
• Odwala omwe ali ndi vuto lalikulu la chiwindi ndi impso (giredi 3),
• Oledzera komanso oledzera (kuwopseza hypoglycemia).

Ndi kuledzera, kuledzera kwamphamvu kwa glibenclamide kumatheka, ndipo mkhalidwe wa kuledzera umaphimba zizindikiro za tsoka lomwe likubwera.

Ndi ntchito zam'mimba, kuvulala kwambiri, kuwotcha kwambiri, kumwa mapiritsi aliwonse a antidiabetes ndi oletsedwa. Amasinthidwa kwakanthawi ndi insulin, yomwe imakupatsani mwayi wosintha mosavuta komanso wambiri wa shuga mu plasma.

Palibe choletsa kotheratu pakuwongolera mayendedwe ndi zida zina zovuta panthawi yamankhwala ndi Maninil. Koma kuukira kwa hypoglycemic kumatha kusokoneza chidwi ndi malingaliro, makamaka pakaphatikizidwa ndi mankhwala ochepetsa shuga. Chifukwa chake, kuchuluka kwake kwa aliyense wodwala matenda ashuga ayenera kudzipenda.

Zotsatira Zogwiritsa Ntchito Mankhwala

Mankhwala ofanana ndi glibenclamide ndi clonidine, komanso β-adrenergic blockers, reserpine, guanethidine, zizindikiro za hypoglycemia zomwe zikubwera zimaphimbidwa ndipo salola kuti azindikire kuperewera kwa matenda ashuga.

Kugwiritsa ntchito mankhwala osokoneza bongo mosalekeza komwe kumayambitsa kusokonezeka kwa chopondapo kumachepetsa shuga m'magazi ndikukulitsa mwayi wa hypoglycemia.

Limbikitsani kuthekera kwa glibenclamide mpaka kugunda kwa hypoglycemic, mutha kugwiritsa ntchito kufanana kwa insulin, ma inhibitors a ACE, mapiritsi ochepetsa shuga, mankhwala ozikidwa ndi mahomoni achimuna, mankhwala osokoneza bongo, antidepressants, β-blockers, clofibrate, mankhwala ozikidwa pa quinolone, coumarin, phenamine, disaminophen miconazole, PASK, pentoxifylline, perhexylin, pyrazolone, phenenecid, salicylates, sulfonamidamide mankhwala, maantibayotiki a kalasi ya tetracycline, tritokvalin, cytost tics.

Imalepheretsa ntchito ya mankhwala, kupititsa patsogolo machitidwe a hyperglycemic, kugwiritsa ntchito pamodzi kwa acetazolamides, β-adrenergic blocking agents, diazoxide, glucagon, barbiturates, okodzetsa, tubazide, glucocorticosteroids, phenothiazine gulu la mankhwala, phenytoin, nicotinatesimocampinate, mankhwala a panctoinin chithokomiro.

Mankhwala a gulu la Coumarin, ranitidine, gastric H2 receptor antagonists, pentamidine, reserpine amachita mosaganizira, kumakhala ngati othandizira kapena oletsa zochitika za glibenclamide.

Kuthandiza ndi bongo

Mankhwala osokoneza bongo a glibenclamide (onse omwe ali pachimake komanso omwe amakwiya) amapereka hypoglycemia yayitali - ndi mphamvu yayitali, yoopsa komanso yoopsa ya wozunzidwayo. Mawonetsedwe azachipatala a matenda a hypoglycemic, aliyense wodwala matenda ashuga ayenera kuzindikira molondola:

• Njala yosalamulirika
• Manja ndi miyendo,
• Tachycardia
• Kuchulukitsa nkhawa
• Khungu loyera ndi mucous nembanemba.

Nthawi zina pali zovuta zosakhalitsa za chikumbumtima, paresthesia. Ngati wovutikayo sanapatsidwe chithandizo chamankhwala mwadzidzidzi, amayamba kudwala matenda opweteka kwambiri.

Kuzindikira za zotulukazi kumayamba ndi kusonkha zidziwitso za wovutikayo kuchokera kwa achibale odziwika ndi mankhwala omwe wodwala matenda ashuga ndi matenda ake adatenga. Kuyesedwa kwa labotale kumachitika.

Kuyang'ana kwa wolakwiridwayo kumakupatsani mwayi wofufuza momwe khungu limakhalira (kuzizira, kusakhazikika, kunyowa). Matenthedwe amatha kukhala abwinobwino kapena otsika. Kutengera kuzunza kwa kuukira, minyewa yam'mimba ya mtundu wa tonic kapena clonic, mawonekedwe osakhazikika, komanso kukomoka kumawonedwa.

Ngati wozunzidwayo akadali ndi chidwi, amatha kumwa tiyi wokoma ndi shuga wokhazikika, kudya zakudya zilizonse zothamanga (maswiti, makeke). Ngati vuto silinakhazikika, odwala matenda ashuga amagonekedwa m'chipatala.
Ndi chikomokere kuchipatala, yankho la shuga 40% (40 ml) limayendetsedwa iv. Moyang'aniridwa ndi mayeso a labotale, kulowetsedwa kwa mothandizidwa ndi ochepa maselo owonjezera amtole asintha.

Milandu ya hypoglycemic yomwe imakhala nthawi yayitali komanso kuchedwetsa imadziwika, ikulimbikitsidwa ndikuwonjezereka kwa glibenclamide. Zinthu ngati izi zimafunikira kuti wodwala azimugonekera kuchipatala kwa masiku 10 kapena kupitiliza kuyang'anitsitsa glycemia komanso chizindikiro cha mankhwala.

Ngati wozunzidwayo amatenga mapiritsi owonjezera kamodzi mwangozi, ndikokwanira kutsuka m'mimba, perekani kwa munthu yemwe amamwa komanso kapu ya tiyi wokoma kapena madzi.

Mitu ya mankhwalawa

Ndi gawo lomwelo la Glibenclamide, Glibenclamide ndi Glibamide ikhoza kulowa m'malo mwa Maninyl. Zizindikiro, contraindication, zoyipa ndizofanana. Malinga ndi code ya ATX ya 4th ku Maninil, Glidiab, Glyclazide, Diabetes, Glurenorm, yofanana ndi yothandizanso, imatha kukhala fanizo.

Malangizo owonjezera

Kwa odwala okhwima, anthu omwe ali ndi zakudya zochepa zama calorie, asthenics, odwala matenda ashuga okhala ndi chiwindi chofanana ndi matenda a impso, gawo loyambira la Maninil limatsitsidwa pang'ono chifukwa cha chiwopsezo cha hypoglycemia. Ngati odwala matenda ashuga asintha kulemera, moyo, njira ya chithandizo ikuwunikidwanso.

Chisamaliro chofunikira ndichofunika kwa odwala omwe ali ndi vuto la kusowa kwa magazi, matenda amisala komanso zina zomwe zimapangitsa kuti wodwala azigwirizana kwathunthu ndi dokotala. Kufufuza kwamankhwala kwamtunduwu wa odwala kuyenera kuchitika pafupipafupi. Kuunika mawonekedwe onse a momwe mankhwalawo amathandizira pakhungu, amalemberatu kale mankhwala omwe angatulutsidwe mwachangu ndi zinthu zomwe zimagwira.

Ngati wodwalayo satenga metformin, amapatsidwa mankhwala a glitazone monga rosiglitazone kapena pioglitazone. Ndi zowunikira zoyenera, mapiritsi a Maninil amathandizidwanso ndi mankhwala othandizira odwala omwe ali ndi vuto lina lililonse. Guarem kapena Acarbose, omwe, monga Maninil, amathandizira kapamba, sagwiritsira ntchito mankhwala ovuta.

Kugwiritsa ntchito nthawi yayitali kwa glibenclamide kumachotsa β-maselo, kumabweretsa necrosis, ndikuyamba kukhala wopanda tanthauzo kwa Maninil. Kuthandizira kapamba, wodwalayo amasamutsidwa kupita ku insulin (kwathunthu kapena pang'ono, kutengera mlingo wa atrophy yawo).

Kuunikira kwa mankhwala kwa madokotala ndi odwala matenda ashuga

About ndemanga za Maninil ndizosakanikirana. Madotolo amati ndi mankhwala achikhalidwe cha hypoglycemic okhala ndi umboni wamphamvu wokhala chithandizo ndi chitetezo. Anthu odwala matenda ashuga sakhutira ndi kuwonjezereka kwakanthawi kotsimikizika komanso zotsatira zina zoyipa, koma kuwunika mphamvu ya mankhwalawa malinga ndi zotsatira za wodwala wina sikutha.

Malangizo omwe ali patsamba lino ndi malangizidwe osinthika a malangizo ovomerezeka, omwe cholinga chake ndi kuwazolowera, osati kuti mudzipangire nokha. Kusankhidwa kwa mankhwalawa komanso kukonzekera njira zamankhwala ndizovomerezeka kwa dokotala.

Kufotokozera Maninil ndi mawonekedwe ogwiritsa ntchito

Maninil ndi mankhwala a mtundu 2 omwe samatengera insulin. Ndi piritsi ya pinki yoyendetsera pakamwa.

Kuchita kwa mankhwalawa kumadalira kukondoweza kwa kupanga kwa insulin ndi kapamba komanso kuwonjezeka kwa chidwi chake. Zotsatira zake, insulin imamasulidwa kwambiri ndipo zotulukapo zake zimakonzedwa. Mankhwala amachepetsa glycogenolysis (kuwonongedwa kwa glycogen mpaka glucose) ndi gluconeogeneis (kaphatikizidwe ka shuga kuchokera ku zinthu zopanda mafuta m'thupi) m'chiwindi. Izi zimakuthandizani kuti muchepetse kuchepa kwa shuga m'magazi.

Maninil amachepetsa kuwopsa kwa matenda a shuga a mtundu wachiwiri - kuwonongeka kwa mitsempha, masomphenya, mtima, mtsempha wamagazi.

Lemberani mankhwala pokhapokha kuchepa thupi, kudya komanso kuchita masewera olimbitsa thupi sikunabwezeretse kagayidwe kachakudya mthupi.

Maninil akhazikika shuga wamagazi pamlingo wachilengedwe

Mankhwala ayenera kuperekedwa ndi endocrinologist. Mlingo umatsimikizika pambuyo pakupenda komanso shuga ndimagazi ndikuwunika mkodzo ndipo umatha kusintha pakapita nthawi.

Kutulutsa mawonekedwe ndi kapangidwe kake

Chomwe chimagwira ndi glibenclamide.

Piritsi limodzi la Maninil lili ndi 1.75 mpaka 5 mg ya glibenclamide.

Chifukwa cha mitundu yosiyanasiyana ya kumasulidwa, ndikosavuta kusankha mlingo woyenera womwe uli woyenera pachilichonse chithandizo cha matendawa. Pogulitsa mutha kupeza zotsatirazi:

• 1.75 mg - 120 ma PC. (120 rub.),
• 3,5 mg - ma PC. (160 rub.),
• 5 mg - ma PC 120. (135 rub.)

Otsatirawa akupezeka m'mapiritsi omwe ali ndi mulingo wa 1.75 mg ndi 3.5 mg:

• lactose monohydrate,
• wowuma mbatata
• methyl hydroxyethyl cellulose,
• colloidal silicon dioxide,
• magnesium wakuba,
• utoto (E124).

Mapiritsi a 5 mg ali ndi mndandanda wosiyana pang'ono wa omwe adalandira:

• lactose monohydrate,
• magnesium wakuba,
• wowuma mbatata
• utoto (E124),
• talcum ufa
• gelatin.

Contraindication

Maninil amatsutsana pamilandu yotsatirayi:

• mtundu 1 shuga
• kumverera kwa chilichonse mwazigawo
• mavuto akulu a chiwindi ndi impso,
• matumbo,
• hypoglycemic chikomokere ndi mitundu,
• opaleshoni yam'mimba
• paresis am'mimba
• ketoacidosis.

Chipangizocho sichitha kugwiritsidwa ntchito ndi amayi apakati komanso oyamwitsa, ana ndi achinyamata ochepera zaka 18. Maninil amadziwikiranso anthu omwe amadalira mowa kwambiri.

Ndi kuperekera kwa Maninil munthawi yomweyo ndi mowa, zotsatira zoyipa zimatha kuchitika mwa hypoglycemia (dontho lakuthwa la shuga).

Zotheka zoyipa ndi bongo

Ngati atamwa molakwika, Maninil angayambitse matenda oopsa a hypoglycemia, makamaka ngati pali kuchuluka kwa mankhwala osokoneza bongo kapena kumwa molakwika, komanso kumwa mowa kwambiri. Chiwopsezo chimawonjezeka ndi kulimbitsa thupi mwadzidzidzi, kufa ndi njala, kuchepa mphamvu kwa kagayidwe kazakudya (wokhala ndi mavuto a endocrine).

Pa gawo loyambirira la chithandizo, kuwonongeka kwa mawonekedwe kapena chidwi champhamvu cha kuwala kowala kumatha kuchitika. Njirayi imasinthidwa ndipo pakapita nthawi zinthu zonse zimasintha.

Zotsatira zoyipa kuchokera m'matumbo am'mimba sizomwe zimachitika:

Pazochitika zapadera, pamabuka mavuto okhudzana ndikupanga magazi (kusintha kwa kapangidwe ka magazi).

Kuti muchepetse zoopsa zomwe zingachitike, chithandizo cha matenda ashuga omwe ali ndi Maninil ziyenera kuchitika moyang'aniridwa ndi endocrinologist.

Kuwongolera kwakutali kwa Maninil kungakhale ndi chifukwa chakuchepa kwa chithokomiro komanso kuchuluka kwa thupi.

Ngati mutamwa kwambiri Maninil, mutha kupezeka ndi hypoclycemia. Amadziwika ndi kumva mwamphamvu njala, nkhawa, palpitations, pallor khungu. Popanda kuchitapo kanthu moyenera, kukomoka komanso kupweteka kumatha kuchitika, kumawilidwa ndi imfa ya wodwalayo. Chiwembu chogwira ntchito pamavuto ndibwino kukambirana ndi adokotala pasadakhale.

Tcherani khutu! Mankhwala osokoneza bongo ndi owopsa. Khazikitsani mlingo wa tsiku ndi tsiku muyenera kukhala akatswiri pokhapokha pakuwunika. Kudzichitira nokha mankhwala sikovomerezeka.

Malamulo Ovomerezeka

Mosiyana ndi mankhwala ena a hypoglycemic, Maninil ayenera kumwedwa m'mawa mopanda kanthu. Piritsi yonse imatsukidwa ndi kapu yamadzi. Ngati adotolo adalimbikitsa kugawa muyeso wa mankhwala awiri Mlingo wachiwiri, ndiye kuti izi ziyenera kuchitika madzulo, komanso musanadye.

Zofunika! Kuti mukwaniritse bwino, muyenera kumwa mankhwalawo nthawi yomweyo tsiku lililonse. Ndizosavomerezeka kuphonya phwando.

Chifukwa cha mawonekedwe osiyanitsidwa amasulidwe, mu zamakono zamankhwala pali malingaliro makumi awiri ogwiritsira ntchito Maninil. Kutalika kwa mankhwalawa kwa mankhwala kumatsimikiziridwa ndi endocrinologist kutengera mtundu wa wodwala wina. Pa mankhwalawa, kuwunika kwamlungu m'magazi ndi mkodzo kuyenera kuchitika.

Tcherani khutu! Ngati zakudya kapena kuchuluka kwa zolimbitsa thupi kwasintha, muyenera kudziwitsa dokotala. Izi zitha kukhala chifukwa chosinthira mlingo wa mankhwalawo.

Maninil amatha kugwiritsidwa ntchito ndi ma othandizira ena a hypoglycemic (insulin, metformin), mankhwala a anabolic, ma inhibitors a ACE, mahomoni achimuna. Ndi makonzedwe omwe munthawi yomweyo ndimankhwala ena, zotsatira za Maninil zitha kuchuluka kapena kuchepa. Izi ziyenera kuganiziridwa posankha mtundu.

Ngati mankhwala osapambana a Maninil kapena osagwirizana ndi zigawo zake pochiza matenda amtundu wa 2, mankhwala ena amatha kusankhidwa. Pali zojambula (ndi zogwira ntchito) komanso zopanda mawonekedwe (zochizira zotsatira) za Maninil. Tiyeni tiwone ena a iwo.

Kodi ndingasinthe bwanji Maninil - tebulo

Ndemanga za Odwala

Mankhwalawa amaperekedwa kwa odwala omwe ali ndi matenda a shuga a mtundu wa 2. Mankhwalawa adawalamula ndi dokotala kwa agogo athu. Timazipeza mu mankhwala osakira maphikidwe. Mtengo wa mankhwalawa ndi ma ruble 164. Iyenera kuchitika mosamala, monga momwe dokotala wakunenera. Pa phwando, ndikofunikira kuwongolera kuchuluka kwa shuga m'magazi. Idyani nthawi, mwinanso hypoglycemia imayamba. Agogo athuwa akhala akumwa mapiritsiwa kwa miyezi iwiri tsopano. Amamva bwino, amakhala moyo wonse. Mankhwalawa ndi othandiza, amathana bwino ndi ntchito yake.

vbtkjvf333

http://otzovik.com/review_3231064.html

Atsikana, inenso, ndili ndi inu - ndilinso ndi matenda omwewo: kuchepa thupi - shuga akuyandikira zabwinobwino, onjezerani - amatumphuka. Chikumbumtima changa nthawi zonse chimaphimba maso anga ang'ono pomwe atatu a ife (ndi ine, ndi iye komanso matenda a shuga) ayamba kudya. Apa tikuphwanya. Tsopano ndinadzikokeranso palimodzi- ndipo ndinaponyanso pang'ono. Ndimatenga mapiritsi a Maninil 3.5 - 1 musanadye komanso Glucofage 500 kumapeto kwa chakudya m'mawa ndi madzulo. Ndikumva bwino zikhalidwe zanga: ngakhale nditha kudziwa shuga yanga molondola.

chotchinga

http://age60.ru/PRINT-f3-t373.html

Ndipo ndimakonda Maninil, munthu wofuna kudya komanso woganiza bwino, koma, monga momwe akunenera, aliyense kwa wake.

Androlik500

Kuti chithandizo cha matenda a shuga chizigwira bwino, muyenera kutsatira kwambiri zomwe mwatsimikiza. Mlingo wa Maninil umatsimikiziridwa ndi dokotala potengera zotsatira za maphunziro. Mankhwalawa pogwiritsa ntchito mankhwalawa, ndikofunikira kuti mupitirize kuyesedwa kwa glucose ndikupewa kumwa mowa.

Zambiri pa matenda ashuga:

M'mawa ndi masana nditatha kudya, ndimatenga mapiritsi amodzi ndi theka a maninil 3.5 m / g, i.e. 10,5 m / g patsiku. Ndimadya chilichonse, i.e. Ndimadyanso maswiti. Ndimayang'ana shuga m'magazi m'mimba yopanda kanthu. Ndi zakudya komanso chithandizo chotere, kuchuluka kwa shuga sikudutsa 6.5 m / mol. Zizindikiro za matenda ashuga sizitsatiridwa - kulemera, kuyamwa, kukoka pafupipafupi, kufooka, ludzu. Adadzikhazikitsira yekha. Ndikudziwa kuti dongosololi silili lolondola ndipo mwina ndikutenga manila ochulukirapo. Ndiuzeni momwe ndingachitire.

Classified (mndandanda) wa mankhwala ochepetsa shuga a matenda a shuga a 2

Popeza pali mankhwala ambiri kuti muchepetse magazi, ndidaganiza kuti ndikudziwitseni. Pomwepo ndi aliyense m'nkhaniyi. Kuti muchite bwino, ndikuwonetsa m'mabakhu dzina lodziwika kwambiri lazamalonda, koma kumbukirani kuti pali ena ambiri. Tsopano ndi awa:

1. Gulu la Biguanide ndi woimilira ndi metformin (siofor).
2. Gulu la sulfonylurea ndi oimira ake ndi glibenclamide (maninyl), glyclazide (diabeteson mv 30 ndi 60 mg), glimepiride (amaryl), glycidone (glurenorm), glipizide (minidiab).
3. Gulu loumbidwa ndi dongo ndi womuimira yekhayo ndi repaglinide (novonorm).
4. Gulu la thiazolidinedione ndi oimira ake ndi rosiglitazone (avandium) ndi pioglitazone (actos).
5. Gulu la alpha-glucosidase inhibitors ndipo woimilira ndi acarbose (glucobai).
6. Gulu la dipeptidyl peptidase-4 inhibitors (DPP-4) ndi oimira ake ndi vildagliptin (galvus), sitagliptin (Januvia), saxagliptin (onglise).
7. Gulu la agonists ofanana ndi glucone-1 peptide-1 (GLP-1) ndi oimira ake ndi exenatide (byeta), liraglutide (ushindi).
8. Malangizo Gulu la zoletsa za sodium-glucose-cotransporter mtundu 2 inhibitors (SGLT2 inhibitors) - dapagliflozin (Forsig), canagliflozin (Attokana), empagliflosin (Jardian)

Mankhwala ochepetsa magazi a Biguanide

Gulu lalikulu la Biguanide limayimirira podium la mankhwala onse ochepetsa shuga a matenda ashuga a 2.

Woimira yekhayo ndi metformin. Mankhwala ochokera pagululi ali ndi zotumphukira, amachepetsa kukana kwa insulin. Koma, monga zidachitika, ali ndi zotsatirapo zina zabwino, mwachitsanzo, zimagwiritsidwa ntchito pochepetsa thupi komanso kuchepa thupi.

M'nkhani yanga "Metformin - malangizo ogwiritsira ntchito" Sindinangofotokoza mwatsatanetsatane wa mankhwalawa kuti ndichepetse kuchuluka kwa shuga m'magazi a anthu odwala matenda ashuga, komanso ndikufalitsa mndandanda wamazina azamalonda ndi analogues.

Ndipo m'nkhaniyi "Metformin yochepetsa thupi: zabwino zonse ndi zoipa" Ndalemba za kugwiritsa ntchito mankhwalawa pofuna kuchepetsa thupi.

Mankhwala a shuga a magazi ochokera ku gulu la sulfonylurea

Mankhwala a shuga a magazi ochokera ku gulu la sulfonylurea. Ili ndi gulu lalikulu kwambiri, lomwe linapangidwa kalekale. mu kapangidwe kawo ali ndi mapiritsi akale kwambiri okhala ndi glibenclamide (maninyl), a m'badwo watsopano, wofanana ndi glimepiride (amaryl).

Mapiritsi ochepetsa shuga omwe amachokera ku sulfanylurea amakhala ndi mphamvu yolimbikitsira kapamba ndipo sakhala oyenera kwa odwala matenda ashuga a mtundu wachiwiri.

Pakadali pano pali nkhani imodzi yokha "Diabeteson mv 30 ndi 60 mg pochiza matenda ashuga", koma posachedwa pazikhala zofalitsa pa oyimilira ena, motero ndikulimbikitsani kuti mulembetsere zolemba zatsopano kuti musaphonye zofalitsa.

Alfa glucosidase zoletsa - mapiritsi okhala ndi shuga wambiri

Woimira gulu la alpha-glucosidase inhibitors - m'mimba ya m'mimba - imalepheretsa kuyamwa kwa mafuta ndipo potero amachepetsa shuga.

Woimira yekhayo ndiye acarbose (Glucobay). Sichofunikira pakamwa lachiwiri la matenda ashuga 2, koma othandizira, chifukwa alibe mphamvu yotsatsira shuga.

Acarbose nthawi zambiri amaphatikizidwa ndi mankhwala ena. Werengani za mankhwalawa omwe amachepetsa shuga m'magazi "Acarbose ndi zonse zokhudzana ndi izi."

Izi ndi zonse zomwe ndikufuna kukuwuzani lero. M'nkhani yanga yotsatira ndipitiliza nkhani ya mankhwala ochepetsa shuga a gulu la sulfonylurea ndi magulu ena. Ngati muli ndi mafunso kapena kuwonjezera, chonde lankhulani ndemanga. Ndipo pamenepa ndikulankhulani. Bye!